|  | Year | Event(s) | 
| 1 | 1846 | Dr. William Morton, a Massachusetts dentist, is the first to use anesthesia for tooth extraction.
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| 2 | 1847 | Hungarian, Ignaz Semmelweis invents antisceptics.Telegraph line installed between Pittsburgh and Cleveland.
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| 3 | 1849 | Street lights are installed in Cleveland.Walter Hunt invents the safety pin.Zachary Taylor president of the USA 1849-1850.  Zachary Taylor died while in office.
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| 4 | 1850 | Joel Houghton was granted the first dishwasher patent.Millard Fillmore president of the USA 1850-1853.  Millard Fillmore, vice president under Zachary Taylor, sworn in as president after Taylor's death.
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| 5 | 1851 | Isaac Singer invents a sewing machine.
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| 6 | 1853 | Franklin Pierce president of the USA 1853-1857.
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| 7 | 1854 | John Tyndall demonstrates the principles of fiber optics.
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| 8 | 1855 | Isaac Singer patents the sewing machine motor.
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| 9 | 1856 | Cleveland water system goes into operation.Louis Pasteur invents pasteurisation.
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| 10 | 1857 | George Pullman invents the Pullman Sleeping Car for train travel.James Buchanan president of the USA 1857-1861.
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| 11 | 1858 | First sewers in Cleveland. (Where did everything go prior to this?)Hamilton Smith patents the rotary washing machine.Jean Lenoir invents an internal combustion engine.
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| 12 | 1861 | Abraham Lincoln president of the USA 1861-1865.Elisha Otis patents elevator safety brakes, creating a safer elevator.Linus Yale invents the Yale lock or cylinder lock.USA Civil War begins.
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| 13 | 1862 | Alexander Parkes invents the first man-made plastic.Dr. Richard Gatling patents the machine gun.
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| 14 | 1863 | Cleveland starts home delivery of mail.
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| 15 | 1865 | Abraham Lincoln shot by John Wilkes Booth on 14 Apr 1865 and dies the next day.Andrew Johnson president of the USA 1865-1869.  Andrew Johnson, vice president under Abraham Lincoln, sworn in as president upon Lincoln's death.
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| 16 | 1866 | Alfred Nobel invents dynamite.Englishmen Robert Whitehead invents a torpedo.J. Osterhoudt patents the tin can with a key opener.
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| 17 | 1867 | Christopher Scholes invents the first practical and modern typewriter.
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| 18 | 1868 | George Westinghouse invents air brakes.J P Knight invents traffic lights.Robert Mushet invents tungsten steel.
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| 19 | 1869 | Ulysses Grant president of the USA 1869-1877.
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| 20 | 1872 | A.M. Ward issues the first mail-order catalog.J.S. Risdon patents the metal windmill.
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| 21 | 1873 | Joseph Glidden invents barbed wire.
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| 22 | 1874 | American, C. Goodyear, Jr. invents the shoe welt stitcher.
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| 23 | 1876 | Alexander Graham Bell patents the telephone.Melville Bissell patents the carpet sweeper.Nicolaus August Otto invents the first practical four-stroke internal combustion engine.
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| 24 | 1877 | Eadweard Muybridge invents the first moving pictures.Rutherford Hayes president of the USA 1877-1881.Thomas Edison invents the cylinder phonograph or tin foil phonograph.
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| 25 | 1878 | Sir Joseph Wilson Swan was the first person to invent a practical and longer-lasting electic lightbulb.
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| 26 | 1880 | Englishmen, John Milne invents the modern seismograph.The British Perforated Paper Company invents a form of toilet paper.
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| 27 | 1881 | Alexander Graham Bell invents the first crude metal detector.Chester A. Arthur president of the USA 1881-1885.  Chester A. Arthur, vice president under James Garfield, sworn in as president upon the death of Garfield.David Houston patents the roll film for cameras.Edward Leveaux patents the automatic player piano.James Garfield president of the USA 1881.  James Garfield wounded by assassin's bullet on 3 Jul 1881 and dies 19 Sep 1881.
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| 28 | 1884 | Charles Parson patents the steam turbine.George Eastman patents paper-strip photographic film.James Ritty invents the first working, mechanical cash register.Lewis Edson Waterman invents the first practical fountain pen.
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| 29 | 1885 | Gottlieb Daimler invents the first gas-engined motorcycle.Grover Cleveland president of the USA 1885-1889.Harim Maxim invents a machine gun.Karl Benz invents the first practical automobile to be powered by an internal-combustion engine.
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